Shortcuts

Submission Preparation Checklist	Results	Structure Drawing Preferences for Chemical Structures
Cover Letter	Discussion	Drawing Settings
Manuscript Preparation	Conclusion	Text Settings
Sections in Manuscripts	Greek Symbols and Special Characters	Under the Preference Choose
Title	Supplementary Material	Under Page Setup Use
Title Page	References	Tables
Structured Abstract	Figures/Illustrations	Acknowledgments
Keywords	Scaling/Resolution	Conflict of Interest Statement
Text Organization	Formats of Illustrations	Privacy Statement
Section Headings	Image Conversion Tools	Language and Editing
Introduction	Color Figures/Illustrations	Copyright Notice
Materials and Methods	Chemical Structures

 

Submission Preparation Checklist

As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

• The submission has never been published, nor is it considered by another journal at the time INNOSC Theranostics and Pharmacological Sciences is processing and/or reviewing the manuscript. The authors need to notify the journal if the data in the manuscript has been presented at conferences, seminars or other forums.
• The works as described in the manuscript are in line with the Focus and Scope of the journal. The manuscript was written according to the criteria, format and style such as the stylistic and bibliographic requirements set by INNOSC Theranostics and Pharmacological Sciences (see Author Guidelines). All sections of the manuscript are correctly organized.
• The authors have already proofread the manuscript to ensure that either American English or British English has been used consistently throughout the manuscript, the sentences are grammatically correct and no typographical errors are made.
• Cover letter and a list of suggested reviewers (two to five reviewers) have already been included in the manuscript as a document.

Cover Letter

A cover letter directed to the Editor-in-Chief should be submitted along with the manuscript. In other words, the cover letter should combine with the manuscript to become one document before submission to the system.

Authors should indicate clearly the title of the manuscript, the article type, and the specialty to which the manuscript is being submitted, and whether it is part of a research topic. Authors should also include a declaration statement that the manuscript has not been submitted for publication elsewhere; any closely related works submitted for consideration in other publications should be noted and authors may be asked to provide a copy.

It is essential as well that you provide a short description of the objective(s), the significance of the manuscript, as well as impact and novelty of the written works in the relevant field. This will assist the Editor-in-Chief to determine whether your manuscript fits within the scope of a specialty as defined in its mission statement; a detailed cover letter will also facilitate the identification of the Editorial Board Members/Editors and Reviewers most appropriate to evaluate your work, eventually accelerating your manuscript's initial consideration.

Manuscript Preparation  

The manuscript should be written in either American or British English in a clear, direct and active and consistent style. All pages must be numbered sequentially, facilitating the reviewing and editing of the manuscript. It is advisable that authors prepare their manuscript by using the Journal Template provided. 

Sections in Manuscripts

Manuscripts submitted for consideration of publication for original research and review articles in the journal should be divided into the following sections:

• Title
• Title page
• Abstract
• Keywords
• Text Organization
• List of Abbreviations
• Consent for Publication
• Acknowledgments
• Conflict of Interest
• References
• Figures/Illustrations (if any)
• Chemical Structures (if any)
• Tables (if any)
• Supportive/Supplementary Material (if any) 

Title

The title of the article should be precise and brief (less than 120 characters) and fully represents the submitted manuscript. Authors should avoid the use of non-standard abbreviations. The first letter of each word should be in capital letters except for articles, conjunctions and prepositions. 

Title Page

The title page should include an article title, author(s) full name and affiliation, corresponding author(s) names complete affiliation/address, along with phone, fax, and email. 

Structured Abstract

The abstract of an article should be a clear, concise and accurate summary of the submitted manuscript. It should cover the background, objective, results, and conclusion. The length of the abstract should not more than 250 words. Use of abbreviations should be avoided and the references should not be cited in the abstract. A structured abstract is required for Original Research Article with the following sub-headings:

• Background
• Objective
• Methods
• Results
• Conclusion

 Keywords

5 to 8 keywords must be provided. 

Text Organization

The main text should begin on a separate page and should be divided into title page, abstract and the main text. For research articles, the manuscript should begin with the title page and abstract followed by the main text, which must be structured into separate sections as introduction, materials and methods, results, discussion, and conclusion, consent for publication, acknowledgments, conflict of interest, list of abbreviations (if any) and references.

For Review, the manuscript should be divided into title page, abstract, introduction and main text. The main text may be subdivided further according to the areas to be discussed, which should be followed by the consent for publication, acknowledgments, conflict of interest, list of abbreviations (if any) and references sections. The review article should mention any previous important reviews in the field and contain a comprehensive discussion starting with the general background of the field. It should then proceed by discussing the prominent features of recent developments. The authors should avoid presenting material which has already been published in a previous review.

Authors are advised to present and discuss their observations in brief. The manuscript style must be uniform throughout the text with the following requirements

1. Text font size: 10 pt
2. Text font: Times New Roman
3. The full term for an abbreviation should precede its first appearance in the abstract and text unless it is a standard unit of measurement.
4. The reference numbers should be given in square brackets in the text.
5. Italics should be used for Binomial names of organisms (Genus and Species) for emphasis and for unfamiliar words or phrases. Non-assimilated words from Latin or other languages should also be italicized e.g. in vivo, in vitro, per se, et al. etc. 

Section Headings

Section headings should be numbered sequentially, left aligned and capitalized. Sub-section headings should be in lower-case with their initials capitalized. They should be numbered as 1.1, 1.2, etc.

Introduction

This section should include the background, research problems/gaps and aims of the research in a comprehensive manner. 

Materials and Methods

This section provides details of the methodology used along with information on any previous efforts with corresponding references. Any details for further modifications and research should be included.

Results

The presentation and elaboration on the results should be precise. 

Discussion

This section should explore the significance of the results in the manuscript and discuss the impact of the manuscript in light of recent developments in the field by providing supporting findings and data from other published articles. Extensive citations and discussion of published literature should be avoided.

Conclusion

This section may include a small paragraph summarizing the significant works of the manuscript, presenting the final outcome of the research or suggesting further study or improvement on the topic.

Greek Symbols and Special Characters

Greek symbols and special characters often undergo formatting changes and get corrupted or lost during preparation of the manuscript for publication. To ensure that all special characters used are embedded in the text, these special characters should be inserted as a symbol but should not be a result of any format styling (Symbol font face) otherwise they will be lost during conversion to PDF/XML.

Authors are urged to refer to existing guidelines. These guidelines give an arrangement of suggestions involving a rundown of things pertinent to their particular research plan. Chemical equations, chemical names, mathematical usage, unit of measurements, chemical and physical quantity & units must conform to SI and Chemical Abstracts or IUPAC.

All kinds of measurements should be used only as stated in the International System of Units (SI). 

Supplementary Material

The journal allows the authors to include supportive material, for example a PowerPoint file containing a talk about the study, a PowerPoint file containing additional screenshots, a Word, RTF, or PDF document showing the original instrument(s) used, a video or the original data (SAS/SPSS files, Excel files, Access Db files, etc.) provided it is inevitable or endorsed by the journal's Editor.

The Figure legends of the supportive/supplementary material intended for publication must be numbered and provided by the end of the manuscript after the reference section. Each supplementary file submitted to the journal must name as "Supplementary file 1", etc. Any additional material will not appear in the published articles but a link to the original article will be provided on the website.

Authors must clearly indicate if these files are not for publication but meant for the reviewers'/editors' perusal only.

References

Authors should only use ACS style to list the references. All references should be numbered sequentially [in square brackets] in the text and listed in the same numerical order in the reference section. The reference numbers must double check and be finalized, as well as the bibliography must be fully formatted using professional reference listing software, for examples, Endnote or Reference Manager before submission.

See below a few examples of references listed in the ACS Style:

Journal Reference

[1]  Hong, O. Y.; Noh, E. M.; Jang, H. Y.; Lee, Y. R.; Lee, B. K.; Jung, S. H.; Kim, J. S.; Youn, H. J., Epigallocatechin gallate inhibits the growth of MDA-MB-231 breast cancer cells via inactivation of the beta-catenin signaling pathway. Oncol Lett 2017, 14 (1), 441-446.

[2] Tang, Y.; Wang, Y.; Kiani, M. F.; Wang, B., Classification, Treatment Strategy, and Associated Drug Resistance in Breast Cancer. Clin Breast Cancer 2016, 16 (5), 335-343.

[3] Zhang, W.; Brombosz, S.M.; Mendoza, J.L.; Moore, J.S. A high-yield, one-step synthesis of o-phenylene ethynylene cyclic trimer via precipitation-driven alkyne metathesis. J. Org. Chem., 2005, 70, 10198-10201.

[4] Singh, A.; Settleman, J., EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010, 29 (34), 4741-51.

Book Reference

[1] Crabtree, R. H. The Organometallic Chemistry of the Transition Metals, 3rd Ed.; Wiley & Sons: New York, 2001.

Book Chapter Reference

[1] Wheeler, D.M.S.; Wheeler, M.M. Stereoselective Syntheses of Doxorubicin and Related Compounds In: Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier Science B. V: Amsterdam, 1994; Vol. 14, pp. 3-46.

Conference Proceedings

[1] Jakeman, D.L.; Withers, S.G. E. In: Carbohydrate Bioengineering: Interdisciplinary Approaches, Proceedings of the 4th Carbohydrate Bioengineering Meeting, Stockholm, Sweden, June 10-13, 2001; Teeri, T.T.; Svensson, B.; Gilbert, H.J.; Feizi, T., Eds.; Royal Society of Chemistry: Cambridge, UK, 2002; pp. 3-8.

URL (WebPage)

[1] National Library of Medicine. Specialized Information Services: Toxicology and Environmental Health. sis.nlm.nih.gov/Tox/ToxMain.html (Accessed May 23, 2004).

Patent

[2] Hoch, J.A.; Huang, S. Screening methods for the identification of novel antibiotics. U.S. Patent 6,043,045, March 28, 2000.

Thesis

[1] Mackel, H. Capturing the Spectra of Silicon Solar Cells. PhD Thesis, The Australian National University: Canberra, December 2004.

E-citations

[1] Citations for articles/material published exclusively online or in open access (free-to-view), must contain the accurate Web addresses (URLs) at the end of the reference(s), except those posted on an author's Web site (unless editorially essential), e.g. ˜Reference: Available from: URL.

Some crucial points to take note:

• All references must be placed accurately.
• All authors must be cited and there should be no use of the phrase et al.
• Date of access should be provided for online citations/retrieval.
• Journal names should be abbreviated according to the Index Medicus/MEDLINE.
• Punctuation should be properly applied as mentioned in the examples given above.
• Superscript in the in-text citations and reference section should be avoided.
• Abstracts, unpublished data and personal communications (which can only be included if prior permission has been obtained) should not be given in the references section. The details may, however, appear in the footnotes.
• The authors are encouraged to use a recent version of EndNote (version 4 and above) or Reference Manager (version 10) when formatting their reference list, as this allows references to be automatically extracted.

 

Figures/Illustrations

All authors must strictly follow the guidelines below for preparing illustrations for publication in the journal. Any illustration that is found to be sub-standard, then the manuscripts will be rejected.

Illustrations ought to be implanted in the text and should be numbered sequentially in the correct order. If a figure appears in separate parts in pages, all parts of the figure must be provided in a single composite illustration file. Photographs should be provided with a scale bar if appropriate, as well as high-resolution component files.

Scaling/Resolution

Line Art image type is normally an image based on lines and text. It does not contain tonal or shaded areas. The preferred file format is TIFF or EPS in a resolution of 900-1200 dpi, with the color mode is either Monochrome 1-bit or RGB.

Halftone image type is a continuous tone photograph containing no text. The images should in a TIFF format in a resolution of 300 dpi, with the color mode being RGB or Grayscale.

Combination image type is an image containing halftone, text or line art elements. This type of image should be in the TIFF format in a resolution of 500-900 dpi, with the color mode being RGB or Grayscale.

Formats of Illustrations

Illustrations may be submitted in the following file formats

1. EPS (preferred format for diagrams)
2. PDF (also especially suitable for diagrams)
3. PNG (preferred format for photos or images)
4. Microsoft Word (version 5 and above; figures must be a single page)
5. PowerPoint (figures must be a single page)
6. TIFF
7. JPEG (conversion should be done using the original file)
8. BMP
9. CDX (ChemDraw)
10. TGF (ISISDraw)

The publisher does not process the formats of illustration other than those listed above.

For TIFF or EPS figures with considerably large file size, minimizing the file size during online submission is advisable. Authors may, therefore, convert to JPEG format before submission as these results in significantly reduced file size and upload time, while retaining acceptable quality. In order to maintain acceptable image quality, it is recommended that JPEG files are saved at the High or Maximum quality.

Zipit or Stuffit tools should not be used to compress files prior to submission as the resulting compression through these tools is always negligible.

The journal advises authors that do not submit any following illustration:

• Graphics embedded in word processor (spreadsheet, presentation) document.
• Optimized files optimized for screen use (like GIF, BMP. PICT, WPG) because of the low resolution.
• Files with a too low resolution.
• Graphics that are unreasonably large for the content. 

Image Conversion Tools

There are numerous image conversion tools that are free access and used, equipped for changing over to and from various designs groups, including PNG.

Graphics Converter on the Macintosh, Paint Shop Pro, for Windows, and ImageMagick, accessible on Macintosh, Windows and UNIX stages, are some examples of general devices for picture transformation.

Bitmap pictures (e.g. screen captures) should not be changed over to EPS as these result in a substantially bigger file size than the proportionate JPEG, TIFF, PNG or BMP, and low quality. EPS should just be utilized for pictures created by vector-drawing applications, for example, Adobe Illustrator or CorelDraw. Most vector-drawing applications can be spared in or exported as EPS format. On the off chance that the pictures were initially prepared in an Office application, for example, Word or PowerPoint, unique Office files should be specifically transferred to the site, rather than being changed over to JPEG or another configuration of low quality. 

Color Figures/Illustrations

Any color figure should be prepared in the CMYK format. RGB colors are not acceptable.

Note for authors: The journal would like to main a high-quality publication, thus illustrations submitted in color will be published in color only. If authors do not wish the submitted illustrations to be published in color, please provide the uncolored illustrations instead or indicate at the stage of manuscript acceptance or proofreading. 

Chemical Structures

Chemical structures must be prepared in ChemDraw/CDX and provided as a separate file. 

Structure Drawing Preferences for Chemical Structures

[As according to the ACS style sheet] 

Drawing Settings

Chain angle: 120°

Bond spacing: 18% of width

Fixed length: 14.4 pt (0.500cm, 0.2in)

Bold width: 2.0 pt (0.071cm, 0.0278in)

Line width: 0.6 pt (0.021cm, 0.0084in)

Margin width: 1.6 pt (0.096cm)

Hash spacing: 2.5 pt (0.088cm, 0.0347in) 

Text Settings

Font: Times New Roman / Helvetica

Size: 8 pt 

Under the Preference Choose

Units: points

Tolerances: 3 pixels 

Under Page Setup Use

Paper: US letter

Scale: 100%

 Tables

• Data Tables should be submitted in Microsoft Word table format.
• Each table should include a title/caption being explanatory in it with respect to the details discussed in the table. Detailed legends may then follow.
• Table number in bold font i.e. Table 1, should follow a title. The title should be in small case with the first letter in caps. A full stop should be placed at the end of the title.
• Tables should be embedded in the text exactly according to their appropriate placement in the submitted manuscript.
• Columns and rows of data should be made visibly distinct by ensuring that the borders of each cell are displayed as black lines.
• Tables should be numbered in Arabic numerals consecutively in the order of their citation in the body of the text.
• Tabular data provided as additional files can be submitted as an MS Excel spreadsheet. 

Acknowledgments

Authors are required to include a short text to acknowledge the contributions given by colleagues, institutions, organizations or agencies in supporting the works in the manuscript. Any funding source with the grant number must be stated clearly and acknowledged.

Conflict of Interest Statement

Any personal, professional and/or financial contributions or any potential conflict of interest should be included at the end of the submitted manuscript before the references section. For more information on conflicts of interest, please refer to Editorial Policies.

 Privacy Statement

The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.

Language and Editing

All manuscripts should be written in either American or British English and language consistency is important. Manuscripts submitted containing language inconsistencies will not be published. Authors must seek professional assistance for correction of grammatical, scientific and typographical errors. Authors may submit to the publisher's editorial team to have English language editing of your article before submission. Please contact the editorial office by email to itps@editorial.office.com to get a quote on the total number of words of the article to be edited.